“Nucleic acid drugs” inoshandisa “nucleic acid,” iyo inoreva zvinhu zvakadai seDNA neRNA zvinodzora ruzivo rwemajini, semishonga.Izvi zvinobvumidza kunangana nemamorekuru akadai semRNA ne miRNA asingakwanise kunangana nemishonga yechinyakare yakaderera mamorekuru uye antibody mishonga, uye pane tarisiro huru yemishonga iyi sechizvarwa chinotevera chemishonga.Tsvagiridzo yakasimba iri kuitwa pasi rose sezvo iri kutarisirwa kutungamira mukugadzirwa kwemishonga iyo yaimbove isingagoneki.

Nekune rumwe rutivi, zvakataurwa kuti kugadzirwa kwemishonga inonzi nucleic acid ine nyaya dzekukunda, kusanganisira "(i) kusagadzikana kwe nucleic acid molecules mumuviri," "(ii) kunetseka pamusoro pekusagadzikana kwezvinodhaka," uye "(iii) kuoma muhurongwa hwekuendesa zvinodhaka (DDS)."Zvakare, makambani eJapan ari nhanho kumashure mukugadzirwa kwemishonga yenucleic acid nekuda kwekugadziriswa kwezvibvumirano zvine simba zvenucleic acid nemakambani muEurope neUS, zvichikonzera kukanganisa budiriro yeJapan.

Hunhu hwe nucleic acid zvinodhaka

"Nucleic acid zvinodhaka" ichizvarwa chinotevera chekuwana zvinodhaka tekinoroji ine maitiro akasiyana zvachose pane echinyakare zvigadzirwa zvemishonga.Iyo zvakare inoratidzira kugona kugadzirwa zviri nyore pamamorekuru ane pakati nepakati uye mukana wekuratidza kushanda uye chengetedzo inopfuura iyo yemishonga inorwisa mabhakitiriya.Nekuda kwezvimiro izvi, pane tarisiro yekuti mishonga inonzi nucleic acid ishandiswe mugomarara nezvirwere zvekugara nhaka izvo zvaimbonetsa kurapa, pamwe nezvirwere zvakaita sefuruwenza nehutachiona.

Mhando dze nucleic acid zvinodhaka

Nucleic acid mushonga unoshandisa DNA neRNA unosanganisira iwo akananga nucleic acids padanho rekuti mapuroteni anogadzirwa kubva kugenome DNA (senge mRNA uye miRNA) uye ayo anonanga mapuroteni.

Mhando uye maitiro e nucleic acid zvinodhaka (zvinodhaka zveprophylaxis uye kurapwa)

Kune nucleic acid mishonga ine marudzi akasiyana uye maitiro zvichienderana nezvinangwa uye nzira dzekuita.