Chimiro chazvino chemonkeypox virus
Maererano nenhau dzeWHO musi waChikumi 7, mumavhiki matatu chete (Chivabvu 13 kusvika Chikumi 7), nyaya dzinopfuura chiuru dzetsoko dzakataurwa munyika makumi maviri nenomwe dzisiri dzemonkeypox-endemic.WHO inofunga kuti nyaya dzinogona kushomeka nekuda kweruzivo rushoma rwechirwere uye murabhoritari, uye nyaya dzinogona kuitikawo kune dzimwe nyika.Asi sangano iri rakati richiri kuchengetedza "zvine mwero" ongororo yehutano hwepasi rose yekubuda kwemonkeypox.
Monkeypox, chirwere chezoonotic chinokonzerwa nemonkeypox virus (MPXV), inoonekwa seyakanyanya kukosha chirwere chinotakurwa nehutachiona muvanhu kubva "kupedzwa" kwechibhokisi.Utachiona hwemonkeypox hunokwanisa kutapurirana kubva kumunhu kuenda kumunhu kuburikidza nezvirwere zvinorwara, zvinwiwa zvemuviri, madonhwe ekufema, uye zvinosvibisa, asi nzira iyi yekutapurirana inowanzoda kufambidzana kwenguva refu.
Monkeypox virus ivhairasi yakaputirwa yakapetwa kaviri yeDNA iyo inogona kukura mutsika muAfrica yakasvibira tsoko maseru, zvichikonzera cytopathic mhedzisiro.Hutachiona hunogona kuongororwa nekuongororwa kwakati wandei: enzyme-yakabatana immunosorbent assay (ELISA), antigen yekuongorora bvunzo, polymerase chain reaction (PCR) assay, kana hutachiona hwekuparadzaniswa nesero tsika.
Mufananidzo kubva pawebhusaiti
Isu tiripo kuti tikubatsirei nekubuda kwemonkeypox
Semutengesi wepamba wekutsvagisa molecular biology uye in vitro diagnostic mhinduro, Foregene Biotech yakazvipira kubatsira vekurapa nevesainzi vaongorori kuti vaongorore uye vatsvage hutachiona hwemonkeypox nekukurumidza uye zviri nyore.Foregene Biotech ine inotungamira DNA-chete/RNA-chete yekusunga tekinoroji uye Direct PCR tekinoroji, ichikupa kwakasiyana siyana kutsvagisa kwesainzi uye IVD mbishi zvekutsvaga kwako uye kuongororwa kwehutachiona hwemonkeypox.
Kurudziro yechigadzirwa cheSainzi#
✿ Kucheneswa kwakanaka uye kubviswa kwehutachiona DNA uye RNA
✿ High kuchena, hapana kusvibiswa
✿ Hapana DNase uye RNase inoshandiswa, uye chigadzirwa hachina kuderedzwa
✿ Sangana neakasiyana ezasi ekuyedza maapplication
✿ Inogona kushandiswa kuongororwa kwehuwandu hwematemplate ne fluorescence quantitative PCR, uye inogona kushandiswawo kuona allele.
✿ Yakasarudzika PCR optimization system ine yakasimba kuenderana
✿ Uchishandisa inopisa-kutanga Foregene HS Taq Polymerase, ine yakakwirira amplification kunyatsoita, kunzwa uye hunhu.
#IVD chigadzirwa kurudziro#
✿ Inoshandiswa pakugadzirisa sampuli kuti iongororwe, kuitira kuti nucleic acid iongororwe mumuenzaniso isunungurwe kubva mumamiriro ekusunga nezvimwe zvinhu, uye inogona kushandiswa neForeasy Direct PCR / RT-qPCR zvigadzirwa kuti uwane nokukurumidza kuonekwa.
✿ Kushanda kuri nyore, kukurumidza kugadzirisa kukurumidza, kukwira kwepamusoro, hapana chikonzero chekubvisa system, kuchengetedza nzvimbo nekuvandudza kushanda zvakanaka.
✿ Inokodzera yakakwirira chaiyo PCR, multiplex PCR kuonekwa
✿ Inokodzera genome template kukwidziridzwa ine yakakwira GC zvemukati (> 60%), yakaoma yechipiri chimiro uye yakakura-chiyero genome amplification yekuona.
✿ Iine yakanyanya kupisa-yekutanga chiitiko, kukurumidza kukwidziridzwa uye kutendeka kwakasimba
Nguva yekutumira: Jun-10-2022
